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Article

The association of alpha-fibrinogen Thr312Ala polymorphism and venous thromboembolism in the LITE study.

Thrombosis research - 1 Jan 2007

Rasmussen-Torvik Laura J, Cushman Mary, Tsai Michael Y, Zhang Yan, Heckbert Susan R, Rosamond Wayne D, Folsom Aaron R

Abstract excerpt

INTRODUCTION: The alpha-fibrinogen Thr312Ala variant has been shown to influence clot structure through increased factor XIII cross-linking and formation of thicker fibrin fibers. However, the effect of this common variant on risk of venous thromboembolism (VTE) is unclear. This paper reports the...

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Identifiers

PMID: 17433418
DOI: 10.1016/j.thromres.2007.02.008
PMCID: PMC2679171

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17433418-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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