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Article

Mutants of the Zebrafish K+ Channel Hcn2b Exhibit Epileptic-like Behaviors.

International journal of molecular sciences - 25 Oct 2021

Rodríguez-Ortiz Roberto, Matínez-Torres Ataúlfo

Abstract excerpt

Epilepsy is a chronic neurological disorder that affects 50 million people worldwide. The most common form of epilepsy is idiopathic, where most of the genetic defects of this type of epilepsy occur in ion channels. Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are activated by membrane hyperpolarization, and are mainly expressed in the heart and central and peripheral nervous systems. In...

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Identifiers

PMID: 34768904
DOI: 10.3390/ijms222111471
PMCID: PMC8584164

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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