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Article

Genomewide association analysis of warfarin dose requirements in Middle Eastern and North African populations.

Clinical and translational science - 1 Feb 2022

El Rouby Nihal, Shahin Mohamed H, Bader Loulia, Khalifa Sherief I, Elewa Hazem

Abstract excerpt

To date, there has been no genomewide association study (GWAS) from the Middle East and North African (MENA) region to identify genetic variants associated with warfarin dose variability using this approach. In this study, we aimed to conduct the first GWAS of warfarin dose requirements in patients from the MENA region. A total of 132 Qatari (discovery) and 50 Egyptians (replication) were genotyped using Illumina...

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Share to Cytochrome P-450 CYP2C9

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dose-Response Relationship, Drug

Share to Genome-Wide Association Study

Share to Polymorphism, Single Nucleotide

Share to Vitamin K Epoxide Reductases

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Identifiers

PMID: 34729928
DOI: 10.1111/cts.13176
PMCID: PMC8841446

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