Article
Validation of a proposed warfarin dosing algorithm based on the genetic make-up of Egyptian patients.
Molecular diagnosis & therapy - 1 Dec 2013
Ekladious Sherif M M, Issac Marianne Samir M, El-Atty Sharaf Sahar Abd, Abou-Youssef Hazem S
Abstract excerpt
BACKGROUND: Warfarin is the most frequently prescribed oral anticoagulant worldwide. Due to its narrow therapeutic index and inter-patient variability in dose requirement, this drug has been considered an ideal target for personalised medicine. Several warfarin dosing algorithms have been proposed to tailor the warfarin dosage in the European, Asian and African-American populations. However, minimal interest was...
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