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Article

VKORC1 Asp36Tyr geographic distribution and its impact on warfarin dose requirements in Egyptians.

Thrombosis and haemostasis - 1 Jun 2013

Shahin Mohamed Hossam A, Cavallari Larisa H, Perera Minoli A, Khalifa Sherief I, Misher Anne, Langaee Taimour, Patel Shitalben, Perry Kimberly, Meltzer David O, McLeod Howard L, Johnson Julie A

Abstract excerpt

The VKORC1 Asp36Tyr single nucleotide polymorphism (SNP) is one of the most promising predictors of high warfarin dose, but data on its population prevalence is incomplete. We determined the frequency of this SNP in participants from seven countries on four continents and investigated its effect on warfarin dose requirement. One thousand samples were analysed to define the population prevalence of this SNP. Those...

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Identifiers

PMID: 23571513
DOI: 10.1160/TH12-10-0789
PMCID: PMC3712827

Genes

VKORC1
MAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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