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Article

Genetic and nongenetic factors associated with warfarin dose requirements in Egyptian patients.

Pharmacogenetics and genomics - 1 Mar 2011

Shahin Mohamed Hossam A, Khalifa Sherief I, Gong Yan, Hammad Lamiaa N, Sallam Mohamed T H, El Shafey Mostafa, Ali Shawky S, Mohamed Mohamed-Eslam F, Langaee Taimour, Johnson Julie A

Abstract excerpt

BACKGROUND AND OBJECTIVE: Warfarin is a commonly used oral anticoagulant with a narrow therapeutic index and various genetic and clinical factors that influence interpatient variability in dose requirements. This study investigated the impact of genetic and nongenetic factors on warfarin dose requirements in Egyptians. METHODS: DNA was extracted from 207 patients taking warfarin for more than 2 months and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21228733
DOI: 10.1097/FPC.0b013e3283436b86
PMCID: PMC3038469

Genes

APOE
VKORC1
CALU

Variants

rs2108622

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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