Article
MC1R Is a Prognostic Marker and Its Expression Is Correlated with MSI in Colorectal Cancer.
Current issues in molecular biology - 11 Oct 2021
Peng Lixiong, Chang Jiang, Liu Xilin, Lu Shiying, Ren Honglin, Zhou Xiaoshi, Liu Zengshan, Hu Pan
Abstract excerpt
Melanocortin 1 receptor (MC1R) is thought to be a marker of poor prognosis and a potential target for the treatment of melanoma. Studies have found that MC1R promotes several tumor behaviors, including cell proliferation and differentiation, pigment formation, and genome damage repair. Some single-nucleotide polymorphisms (SNPs) of MC1R are involved in the occurrence and development of melanoma. A few studies...
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