Article
MC1R variants, melanoma and red hair color phenotype: a meta-analysis.
International journal of cancer - 15 Jun 2008
Raimondi Sara, Sera Francesco, Gandini Sara, Iodice Simona, Caini Saverio, Maisonneuve Patrick, Fargnoli Maria Concetta
Abstract excerpt
Melanocortin-1-receptor (MC1R) is one of the major genes that determine skin pigmentation. MC1R variants were suggested to be associated with red hair, fair skin, and an increased risk of melanoma. We performed a meta-analysis on the association between the 9 most studied MC1R variants (p.V60L, p.D84E, p.V92M, p.R142H, p.R151C, p.I155T, p.R160W, p.R163Q and p.D294H) and melanoma and/or red hair, fair skin...
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