Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comprehensive evaluation of allele frequency differences of MC1R variants across populations.

Human mutation - 1 May 2007

Gerstenblith Meg R, Goldstein Alisa M, Fargnoli Maria Concetta, Peris Ketty, Landi Maria Teresa

Abstract excerpt

The melanocortin 1 receptor (MC1R), a member of the G protein-coupled receptors superfamily, mediates the response to melanocortins and is currently the best-described contributor to normal pigment variation in humans. A remarkably large number of natural polymorphisms, or variants, of the MC1R gene have been identified in different populations. Some of these variants have been associated with specific hair and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Biochemical Analysis and Sensing Techniques

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genetics, Population

Share to melanin and skin pigmentation

Share to Receptor, Melanocortin, Type 1

Share to Skin Neoplasms

Share to Skin Protection and Aging

Source

Identifiers

PMID: 17279550
DOI: 10.1002/humu.20476

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comprehensive evaluation of allele frequency differences of MC1R variants across populations.PMID 17279550Read ↗

Melanocortin 1 receptor variants: functional role and pigmentary associations.Semantic proximity Read ↗

Worldwide polymorphism at the MC1R locus and normal pigmentation variation in humans.Semantic proximity Read ↗

The melanocortin-1 receptor gene polymorphism and association with human skin cancer.Semantic proximity Read ↗

Defining the quantitative contribution of the melanocortin 1 receptor (MC1R) to variation in pigmentary phenotype.Semantic proximity Read ↗

Population-based study of natural variation in the melanocortin-1 receptor gene and melanoma.Semantic proximity Read ↗

Assessment of polymorphic variants in the melanocortin-1 receptor gene with cutaneous pigmentation using an evolutionary approach.Semantic proximity Read ↗

Variants of the melanocortin-1 receptor: do they matter clinically?Semantic proximity Read ↗

Melanocortin receptor 1 variants and melanoma risk: a study of 2 European populations.Semantic proximity Read ↗

Identification of four novel melanocortin 1 receptor (MC1R) gene variants in a Mediterranean population.Semantic proximity Read ↗

Melanocortin-1 receptor (MC1R): a review for dermatologists.Semantic proximity Read ↗

The melanocortin 1 receptor (MC1R): more than just red hair.Semantic proximity Read ↗

Skin colour and skin cancer - MC1R, the genetic link.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.