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Article

The Thyroid Hormone Transporter MCT10 Is a Novel Regulator of Trabecular Bone Mass and Bone Turnover in Male Mice.

Endocrinology - 1 Jan 2022

Lademann Franziska, Mayerl Steffen, Tsourdi Elena, Verrey Francois, Leitch Victoria D, Williams Graham R, Bassett J H Duncan, Hofbauer Lorenz C, Heuer Heike, Rauner Martina

Abstract excerpt

Thyroid hormones (TH) are essential for skeletal development and adult bone homeostasis. Their bioavailability is determined by specific transporter proteins at the cell surface. The TH-specific transporter monocarboxylate transporter 8 (MCT8) was recently reported as a regulator of bone mass in mice. Given that high systemic triiodothyronine (T3) levels in Mct8 knockout (KO) mice are still able to cause...

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Identifiers

PMID: 34669927
DOI: 10.1210/endocr/bqab218
PMCID: PMC8598386

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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