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Article

Tissue-specific alterations in thyroid hormone homeostasis in combined Mct10 and Mct8 deficiency.

Endocrinology - 1 Jan 2014

Müller Julia, Mayerl Steffen, Visser Theo J, Darras Veerle M, Boelen Anita, Frappart Lucien, Mariotta Luca, Verrey Francois, Heuer Heike

Abstract excerpt

The monocarboxylate transporter Mct10 (Slc16a10; T-type amino acid transporter) facilitates the cellular transport of thyroid hormone (TH) and shows an overlapping expression with the well-established TH transporter Mct8. Because Mct8 deficiency is associated with distinct tissue-specific alterations in TH transport and metabolism, we speculated that Mct10 inactivation may compromise the tissue-specific TH...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24248460
DOI: 10.1210/en.2013-1800

Genes

TRH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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