Article
Tissue-specific thyroid hormone deprivation and excess in monocarboxylate transporter (mct) 8-deficient mice.
Endocrinology - 1 Sept 2006
Dumitrescu Alexandra M, Liao Xiao-Hui, Weiss Roy E, Millen Kathleen, Refetoff Samuel
Abstract excerpt
Mutations of the X-linked thyroid hormone (TH) transporter (monocarboxylate transporter, MCT8) produce in humans unusual abnormalities of thyroid function characterized by high serum T3 and low T4 and rT3. The mechanism of these changes remains obscure and raises questions regarding the regulatio...
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