Article
Thyroid hormone transporters in health and disease.
Thyroid : official journal of the American Thyroid Association - 1 Aug 2005
Jansen Jurgen, Friesema Edith C H, Milici Carmelina, Visser Theo J
Abstract excerpt
Cellular entry is required for conversion of thyroid hormone by the intracellular deiodinases and for binding of 3,3',5-triiodothyronine (T(3)) to its nuclear receptors. Recently, several transporters capable of thyroid hormone transport have been identified. Functional expression studies using Xenopus laevis oocytes have demonstrated that organic anion transporters (e.g., OATPs), and L-type amino acid...
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