Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular Pathways Involved in Frontotemporal Lobar Degeneration with TDP-43 Proteinopathy: What Can We Learn from Proteomics?

24 Sept 2021

Abstract excerpt

Frontotemporal lobar degeneration (FTLD) is a neurodegenerative disorder clinically characterized by behavioral, language, and motor symptoms, with major impact on the lives of patients and their families. TDP-43 proteinopathy is the underlying neuropathological substrate in the majority of cases, referred to as FTLD-TDP. Several genetic causes have been identified, which have revealed some components of its...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Amyotrophic Lateral Sclerosis Research
Share to Neurological diseases and metabolism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34638637
DOI: 10.3390/ijms221910298

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular Pathways Involved in Frontotemporal Lobar Degeneration with TDP-43 Proteinopathy: What Can We Learn from Proteomics?PMID 34638637Read ↗

The Need for Biomarkers in the ALS–FTD Spectrum: A Clinical Point of View on the Role of ProteomicsSemantic proximity Read ↗

Molecular Neuropathology of TDP-43 ProteinopathiesSemantic proximity Read ↗

The basis of clinicopathological heterogeneity in TDP-43 proteinopathySemantic proximity Read ↗

Transcriptomic analysis of frontotemporal lobar degeneration with TDP-43 pathology reveals cellular alterations across multiple brain regionsSemantic proximity Read ↗

Transcriptomic analysis of frontotemporal lobar degeneration with TDP-43 pathology reveals cellular alterations across multiple brain regionsSemantic proximity Read ↗

Molecular pathways of frontotemporal lobar degeneration.Semantic proximity Read ↗

TDP-43 proteinopathies: a new wave of neurodegenerative diseasesSemantic proximity Read ↗

Frontotemporal lobar degeneration: Pathogenesis, pathology and pathways to phenotype.Semantic proximity Read ↗

TDP-43 proteinopathy in frontotemporal lobar degeneration and amyotrophic lateral sclerosis: From pathomechanisms to therapeutic strategiesSemantic proximity Read ↗

Transcriptomic and pathological analysis of the hnRNP network reveals glial involvement in FTLD pathological subtypesSemantic proximity Read ↗

Proteomic analysis reveals distinct cerebrospinal fluid signatures across genetic frontotemporal dementia subtypesSemantic proximity Read ↗

The molecular basis of frontotemporal dementia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.