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Article

Frontotemporal lobar degeneration: Pathogenesis, pathology and pathways to phenotype.

Brain pathology (Zurich, Switzerland) - 1 Nov 2017

Mann David M A, Snowden Julie S

Abstract excerpt

Frontotemporal Lobar Degeneration (FTLD) is a clinically, pathologically and genetically heterogeneous group of disorders that affect principally the frontal and temporal lobes of the brain. There are three major associated clinical syndromes, behavioral variant frontotemporal dementia (bvFTD), semantic dementia (SD) and progressive non-fluent aphasia (PNFA); three principal histologies, involving tau, TDP-43 and...

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Source

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Identifiers

PMID: 28100023
DOI: 10.1111/bpa.12486
PMCID: PMC8029341

Genes

FUS
GRN
MAPT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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