Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Need for Biomarkers in the ALS–FTD Spectrum: A Clinical Point of View on the Role of Proteomics

9 Jan 2023

Abstract excerpt

Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are severely debilitating and progressive neurodegenerative disorders. A distinctive pathological feature of several neurodegenerative diseases, including ALS and FTD, is the deposition of aberrant protein inclusions in neuronal cells, which leads to cellular dysfunction and neuronal damage and loss. Despite this, to date, the biological...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Amyotrophic Lateral Sclerosis Research
Share to Cholinesterase and Neurodegenerative Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36648959
DOI: 10.3390/proteomes11010001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Need for Biomarkers in the ALS–FTD Spectrum: A Clinical Point of View on the Role of ProteomicsPMID 36648959Read ↗

Proteomic identification of proteins in the human brain: Towards a more comprehensive understanding of neurodegenerative disease.Semantic proximity Read ↗

Biomarker discovery and development for frontotemporal dementia and amyotrophic lateral sclerosisSemantic proximity Read ↗

Proteomic studies in the discovery of cerebrospinal fluid biomarkers for amyotrophic lateral sclerosisSemantic proximity Read ↗

Analysis of circulating protein aggregates reveals pathological hallmarks of amyotrophic lateral sclerosisSemantic proximity Read ↗

Analysis of Circulating Protein Aggregates Reveals Pathological Hallmarks of Amyotrophic Lateral SclerosisSemantic proximity Read ↗

Molecular Pathways Involved in Frontotemporal Lobar Degeneration with TDP-43 Proteinopathy: What Can We Learn from Proteomics?Semantic proximity Read ↗

Network Analysis of the Cerebrospinal Fluid Proteome Reveals Shared and Unique Differences Between Sporadic and Familial Forms of Amyotrophic Lateral SclerosisSemantic proximity Read ↗

Fluid biomarkers in frontotemporal dementia: past, present and futureSemantic proximity Read ↗

Network analysis of the cerebrospinal fluid proteome reveals shared and unique differences between sporadic and familial forms of amyotrophic lateral sclerosisSemantic proximity Read ↗

Altered serum protein levels in frontotemporal dementia and amyotrophic lateral sclerosis indicate calcium and immunity dysregulationSemantic proximity Read ↗

Proteomic biomarker discovery in cerebrospinal fluid for neurodegenerative diseasesSemantic proximity Read ↗

Proteomics Approaches for Biomarker and Drug Target Discovery in ALS and FTDSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.