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Article

BMP pathway regulation of insulin signaling components promotes lipid storage in Caenorhabditis elegans

11 Oct 2021

Abstract excerpt

A small number of peptide growth factor ligands are used repeatedly in development and homeostasis to drive programs of cell differentiation and function. Cells and tissues must integrate inputs from these diverse signals correctly, while failure to do so leads to pathology, reduced fitness, or death. Previous work using the nematode C. elegans identified an interaction between the bone morphogenetic protein...

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PMID: 34634043
DOI: 10.1371/journal.pgen.1009836

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