Article

Intergenerational effects of dietary restriction on insulin/IGF signaling and reproductive development

2018-06-08

Abstract excerpt

The roundworm C. elegans transiently arrests larval development to survive extended starvation ( 1 ), but such early-life starvation reduces reproductive success ( 2, 3 ). Maternal dietary restriction (DR) buffers progeny from starvation, increasing reproductive success ( 4 ). It is unknown why early-life starvation decreases reproductive success and how maternal diet modifies this process. We show here that e...

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Literature Corpus work: ff344319-fca5-5a17-8fa9-2e91e6599b11
DOI: 10.1101/342956

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