Article
A Correlation Between Differentiation Phenotypes of Infused T Cells and Anti-Cancer Immunotherapy.
Frontiers in immunology - 1 Jan 2021
Ren Hao, Cao Kunkun, Wang Mingjun
Abstract excerpt
T-cell therapy, usually with ex-vivo expansion, is very promising to treat cancer. Differentiation status of infused T cells is a crucial parameter for their persistence and antitumor immunity. Key phenotypic molecules are effective and efficient to analyze differentiation status. Differentiation status is crucial for T cell exhaustion, in-vivo lifespan, antitumor immunity, and even antitumor pharmacological...
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