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Article

Expression of LOX Suggests Poor Prognosis in Gastric Cancer

14 Sept 2021

Abstract excerpt

Background: Lysyl oxidase (LOX) is a key enzyme for the cross-linking of collagen and elastin in the extracellular matrix. This study evaluated the prognostic role of LOX in gastric cancer (GC) by analyzing the data of The Cancer Genome Atlas (TCGA) and the Gene Expression Omnibus (GEO) dataset. Methods: The Wilcoxon rank-sum test was used to calculate the expression difference of LOX gene in gastric cancer and...

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PMID: 34595188
DOI: 10.3389/fmed.2021.718986

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