Article
Proteomic Identification of a Gastric Tumor ECM Signature Associated With Cancer Progression
1 Mar 2022
Abstract excerpt
The extracellular matrix (ECM) plays an undisputable role in tissue homeostasis and its deregulation leads to altered mechanical and biochemical cues that impact cancer development and progression. Herein, we undertook a novel approach to address the role of gastric ECM in tumorigenesis, which remained largely unexplored. By combining decellularization techniques with a high-throughput quantitative proteomics...
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