LUM Expression and Its Prognostic Significance in Gastric Cancer

Abstract excerpt

Background. Lumican (LUM) is a member of the small leucine-rich proteoglycan family, and plays dual roles as an oncogene and a tumor suppressor gene. The effect of LUM on tumors is still controversial. Methods. Gene expression profiles and clinical data of gastric cancer (GC) were downloaded from The Cancer Genome Atlas (TCGA) database. The expression difference of LUM in GC tissues and adjacent nontumor tissues...

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