Lysyl oxidase G473A polymorphism is closely associated with susceptibility to gastric cancer in a South Korean population.

doi:10.1111/j.1600-0463.2011.02802.x

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Lysyl oxidase G473A polymorphism is closely associated with susceptibility to gastric cancer in a South Korean population.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Nov 2011

Yoon Jung Hwan, Park Jong Kyung, Kang Young Hwi, Park Yong Kyu, Nam Suk Woo, Lee Jung Young, Park Won Sang

Abstract excerpt

The aim of this study was to determine whether a single nucleotide polymorphism at G473A (rs1800449) within the LOX-propeptide is associated with susceptibility to gastric cancer. We investigated the genotype and allele frequencies of this gene in tissue specimens from 458 gastric cancer patients and 282 healthy individuals. Polymorphism analysis was performed by amplifying the propeptide region of LOX and...

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PMID: 21995629
DOI: 10.1111/j.1600-0463.2011.02802.x

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