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Article

RNAi methods and screening: RNAi based high-throughput genetic interaction screening.

Methods in cell biology - 1 Jan 2011

Cipriani Patricia G, Piano Fabio

Abstract excerpt

Expanding on decades of mutational analyses, numerous genome-scale RNAi screens have now been performed in C. elegans, leading to estimates that the majority of genes with essential functions that can be revealed by single-gene perturbations have already been identified in this organism. To build on this basic foundation and uncover condition-dependent or combinatorial effects of non-essential genes will require...

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PMID: 22118275
DOI: 10.1016/B978-0-12-544172-8.00004-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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