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Article

The art and design of genetic screens: caenorhabditis elegans.

Nature reviews. Genetics - 1 May 2002

Jorgensen Erik M, Mango Susan E

Abstract excerpt

The nematode Caenorhabditis elegans was chosen as a model genetic organism because its attributes, chiefly its hermaphroditic lifestyle and rapid generation time, make it suitable for the isolation and characterization of genetic mutants. The most important challenge for the geneticist is to design a genetic screen that will identify mutations that specifically disrupt the biological process of interest. Since...

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PMID: 11988761
DOI: 10.1038/nrg794

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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