Article
Comprehensive functional genomics using Caenorhabditis elegans as a model organism.
Proceedings of the Japan Academy. Series B, Physical and biological sciences - 1 Jan 2017
Mitani Shohei
Abstract excerpt
We have been working on functional genomics using C. elegans as a model organism. We first used cell-type specific markers and preexisting mutants to investigate how genotype-phenotype causal relationships are regulated. With the aid of transgenic methods, we analyzed various biological processes in C. elegans. We have developed efficient methods to isolate gene knockout strains. Thousands of strains isolated...
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