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Article

Structural Changes in the Cap of Rv0183/mtbMGL Modulate the Shape of the Binding Pocket.

Biomolecules - 1 Sept 2021

Grininger Christoph, Leypold Mario, Aschauer Philipp, Pavkov-Keller Tea, Riegler-Berket Lina, Breinbauer Rolf, Oberer Monika

Abstract excerpt

Tuberculosis continues to be a major threat to the human population. Global efforts to eradicate the disease are ongoing but are hampered by the increasing occurrence of multidrug-resistant strains of Mycobacterium tuberculosis. Therefore, the development of new treatment, and the exploration of new druggable targets and treatment strategies, are of high importance. Rv0183/mtbMGL, is a monoacylglycerol lipase of...

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PMID: 34572512
DOI: 10.3390/biom11091299
PMCID: PMC8472722

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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