Article
Crystal structure of the Saccharomyces cerevisiae monoglyceride lipase Yju3p.
Biochimica et biophysica acta - 1 May 2016
Aschauer Philipp, Rengachari Srinivasan, Lichtenegger Joerg, Schittmayer Matthias, Das Krishna Mohan Padmanabha, Mayer Nicole, Breinbauer Rolf, Birner-Gruenberger Ruth, Gruber Christian C, Zimmermann Robert, Gruber Karl, Oberer Monika
Abstract excerpt
Monoglyceride lipases (MGLs) are a group of α/β-hydrolases that catalyze the hydrolysis of monoglycerides (MGs) into free fatty acids and glycerol. This reaction serves different physiological functions, namely in the last step of phospholipid and triglyceride degradation, in mammalian endocannabinoid and arachidonic acid metabolism, and in detoxification processes in microbes. Previous crystal structures of MGLs...
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