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Article

Dissecting the role of critical residues and substrate preference of a Fatty Acyl-CoA Synthetase (FadD13) of Mycobacterium tuberculosis.

PloS one - 21 Dec 2009

Khare Garima, Gupta Vibha, Gupta Rakesh K, Gupta Radhika, Bhat Rajiv, Tyagi Anil K

Abstract excerpt

Newly emerging multi-drug resistant strains of Mycobacterium tuberculosis (M.tb) severely limit the treatment options for tuberculosis (TB); hence, new antitubercular drugs are urgently needed. The mymA operon is essential for the virulence and intracellular survival of M.tb and thus represents an attractive target for the development of new antitubercular drugs. This study is focused on the structure-function...

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PMID: 20027301
DOI: 10.1371/journal.pone.0008387
PMCID: PMC2793005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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