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Article

Exome sequencing identifies new somatic alterations and mutation patterns of tongue squamous cell carcinoma in a Chinese population.

The Journal of pathology - 1 Aug 2020

Zhang Heyu, Song Yongmei, Du Zhenglin, Li Xuefen, Zhang Jianyun, Chen Shuai, Chen Feng, Li Tiejun, Zhan Qimin

Abstract excerpt

Tongue squamous cell carcinoma (TSCC) is an aggressive group of tumors characterized by high rates of regional lymph node metastasis and local recurrence. Emerging evidence has revealed genetic variations of TSCC across different geographical regions due to the impact of multiple risk factors such as chewing betel-quid. However, we know little of the mutational processes of TSCC in the Chinese population without...

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Carcinoma, Squamous Cell
Exome
Genes, Tumor Suppressor
Lymphatic Metastasis
Neoplasm Recurrence, Local

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tongue Neoplasms

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PMID: 32432340
DOI: 10.1002/path.5467

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