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Mutational landscape of Japanese patients with oral squamous cell carcinoma from comprehensive genomic profiling tests.

Oral oncology - 1 Dec 2024

Ichimura Norihisa, Urata Yusuke, Kobayashi Takeru, Ebata Ryo, Matsumoto Hiroya, Hibi Hideharu

Abstract excerpt

OBJECTIVES: Oral squamous cell carcinoma (OSCC) is the most common subtype of head and neck squamous cell carcinoma (HNSCC). Treatment options for OSCC are currently limited owing to the lack of identified therapeutic targets. In this study, we aimed to analyze the genomic profiles of Japanese patients with OSCC and compare them to those of patients with HNSCC to identify potential therapeutic targets. MATERIALS...

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Adolescent
Aged, 80 and over
East Asian People
Genomics
Japan

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mouth Neoplasms

Squamous Cell Carcinoma of Head and Neck

Source

Identifiers

PMID: 39432990
DOI: 10.1016/j.oraloncology.2024.107079

Genes

CCND1
CDKN2A
FGF19
TERT
CASP8
CDKN2B
EGFR
HRAS
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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