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Targeted next-generation sequencing of 50 cancer-related genes in Japanese patients with oral squamous cell carcinoma

1 Sept 2018

Abstract excerpt

Somatic mutation analysis is a standard of practice for human cancers to identify therapeutic sensitization and resistance mutations. We performed a multigene sequencing screen to explore mutational hotspots in cancer-related genes using a semiconductor-based sequencer. DNA from oral squamous cell carcinoma samples was used as a template to amplify 207 regions from 50 cancer-related genes. Of the 80 oral squamous...

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PMID: 30226113
DOI: 10.1177/1010428318800180

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