Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Systematic Influence of Circulating Bilirubin Levels on Osteoporosis.

Frontiers in endocrinology - 1 Jan 2021

Zhao Jinqiu, Zhang Muzi, Quan Zhengxue, Deng Liang, Li Yongguo, He Bin

Abstract excerpt

Observational studies report some association between circulating bilirubin levels and osteoporosis, but it is unknown if this association is causal or confounded. In this two-sample Mendelian randomization (MR) study, we included a large genome-wide association study (GWAS) associated with total bilirubin levels among 317,639 people, a large meta-analysis to identify genetic variants associated with bone mineral...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Bilirubin
Share to Bone Density

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Causality

Share to Fractures, Bone

Share to Genome-Wide Association Study

Share to Mendelian Randomization Analysis

Share to Osteoporosis

Source

Open in PubMed Open full text

Identifiers

PMID: 34539572
DOI: 10.3389/fendo.2021.719920
PMCID: PMC8447935

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Systematic Influence of Circulating Bilirubin Levels on Osteoporosis.PMID 34539572Read ↗

No causal effect of serum urate on bone-related outcomes among a population of postmenopausal women and elderly men of Chinese Han ethnicity--a Mendelian randomization study.Semantic proximity Read ↗

The role of total bilirubin in bone mineral density among patients with type 2 diabetes older than 50 yearsSemantic proximity Read ↗

Unravelling genetic causality of haematopoiesis on bone metabolism in human.Semantic proximity Read ↗

Deciphering the interplay between serum urate and bone mineral density: insights from observational and genetic perspectives.Semantic proximity Read ↗

Causal association of NAFLD with osteoporosis, fracture and falling risk: a bidirectional Mendelian randomization studySemantic proximity Read ↗

Association between systemic redox balance and osteoporosis: prospective evidence, polygenic modification, and proteomic and inflammatory mediation in the UK Biobank.Semantic proximity Read ↗

Are blood lipids risk factors for fracture? Integrative evidence from instrumental variable causal inference and mediation analysis using genetic data.Semantic proximity Read ↗

Mendelian randomization analysis to examine for a causal effect of urate on bone mineral density.Semantic proximity Read ↗

Circulating Alpha-Tocopherol Levels, Bone Mineral Density, and Fracture: Mendelian Randomization Study.Semantic proximity Read ↗

Bone biochemical markers, bone mineral density, and the risk of osteonecrosis of the femoral head: a Mendelian randomization study.Semantic proximity Read ↗

Genetically predicted circulating serum homocysteine levels on osteoporosis: a two-sample mendelian randomization study.Semantic proximity Read ↗

Causal associations between osteoporosis and HBV infection across Asian and European populations: evidence from Mendelian randomization and colocalization analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.