Article
Deciphering the interplay between serum urate and bone mineral density: insights from observational and genetic perspectives.
Journal of the International Society of Sports Nutrition - 31 Dec 2026
Xiang Rong, Zhong Yangdan, Zhao Xunying, Deng Qin, Hou Jiaojiao, Sha Linna, Qu Yang, Tang Mingshuang, Zhu Jiangbo, Zheng Sirui, Han Tao, Zhou Jinyu, Yu Ting, Yang Bin, Song Xin, Xia Maoyao, Fan Mengyu, Tao Chenglin, Jiang Xia
Abstract excerpt
BACKGROUND: Urate commonly influences bone metabolism due to its antioxidant properties, yet this relationship remains inadequately understood. Our study aims to investigate both the phenotypic and genetic relationships between urate and heel estimated bone mineral density (eBMD), a proxy marker for osteoporosis. METHODS: Leveraging UK Biobank individual-level data and summary statistics from the hitherto largest...
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