Executive function deficits in genetic frontotemporal dementia: results from the GENFI study

Abstract excerpt

<h4>Background</h4> Executive dysfunction is a core feature of frontotemporal dementia (FTD). Whilst there has been extensive research into such impairments in sporadic FTD, there has been little research in the familial forms. <h4>Methods</h4> 752 individuals were recruited in total: 214 C9orf72 , 205 GRN and 86 MAPT mutation carriers, stratified into asymptomatic, prodromal and fully symptomatic, and 247 mutatio...

Topics

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• C9orf72 Protein
• Cognition
• Cohort Studies
• Frontotemporal Dementia
• Mutation
• Neuropsychological Tests
• Progranulins
• tau Proteins

Identifiers and source

Literature Corpus work

d97e171e-c91c-56b2-a88a-b87f3d88181b

DOI

10.1101/2024.05.16.24307390