Article
Complex structure of the acyltransferase VinK and the carrier protein VinL with a pantetheine cross-linking probe.
Acta crystallographica. Section F, Structural biology communications - 1 Sept 2021
Miyanaga Akimasa, Ouchi Risako, Kudo Fumitaka, Eguchi Tadashi
Abstract excerpt
Acyltransferases are responsible for the selection and loading of acyl units onto carrier proteins in polyketide and fatty-acid biosynthesis. Despite the importance of protein-protein interactions between the acyltransferase and the carrier protein, structural information on acyltransferase-carrier protein interactions is limited because of the transient interactions between them. In the biosynthesis of the...
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