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Article

The proximity between helix I and helix XI in the melibiose carrier of Escherichia coli as determined by cross-linking.

Biochimica et biophysica acta - 1 Oct 2001

Ding P Z, Wilson T H

Abstract excerpt

The melibiose carrier of Escherichia coli is a transmembrane protein that comprises 12 transmembrane helices connected by periplasmic and cytoplasmic loops, with both the N- and C-termini located on the cytoplasmic side. Our previous studies of second-site revertants suggested proximity between several helices, including helices XI and I. In this study, we constructed six double cysteine mutants, each having one...

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Identifiers

PMID: 11557023
DOI: 10.1016/s0005-2736(01)00385-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence.

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The proximity between helix I and helix XI in the melibiose carrier of Escherichia coli as determined by cross-linking.PMID 11557023Read ↗

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