Article
Significance of regional population HLA immunogenetic datasets in the efficacy of umbilical cord blood banks and marrow donor registries: a study of Cretan HLA genetic diversity.
Cytotherapy - 1 Feb 2022
Latsoudis Helen, Stylianakis Emmanouil, Mavroudi Irene, Kanterakis Alexandros, Pavlidis Pavlos, Georgopoulou Anthie, Batsali Aristea, Gontika Ioanna, Fragiadaki Irene, Zamanakou Maria, Germenis Anastasios E, Papadaki Helen A
Abstract excerpt
BACKGROUND AIMS: The high genetic diversity of HLA across populations significantly confines the effectiveness of a donor or umbilical cord blood search for allogeneic hematopoietic stem cell transplantation (HSCT). This study aims to probe the HLA immunogenetic profile of the population of Crete, a Greek region with specific geographic and historical characteristics, and to investigate potential patterns in HLA...
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