Article
HLA diversity in the Argentinian Umbilical Cord Blood Bank: frequencies according to donor's reported ancestry and geographical distribution.
Scientific reports - 18 Feb 2021
Fernández Souto Daniela, Rosello Julieta, Lazo Laura, Veloso Florencia, Gamba Cecilia, Kuperman Silvina, Roca Valeria
Abstract excerpt
Umbilical cord blood (UCB) is a suitable source for hematopoietic stem cell transplantation. The study of HLA genes by next generation sequencing is commonly used in transplants. Donor/patient HLA matching is often higher within groups of common ancestry, however "Hispanic" is a broad category that fails to represent Argentina's complex genetic admixture. Our aim is to describe HLA diversity of banked UCB units...
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