Article
Next generation sequencing of 11 HLA loci characterises a diverse UK cord blood bank.
Human immunology - 1 Jun 2020
Guerra Sandra G, Hamilton-Jones Siobhan, Brown Colin J, Navarrete Cristina V, Chong Winnie
Abstract excerpt
The introduction of next generation sequencing (NGS) for stem cell donor registry typing has contributed to faster identification of compatible stem cell donors. However, the successful search for a matched unrelated donor for some patient groups is still affected by their ethnicity. In this stud...
Topics
- Alleles
- Biodiversity
- Blood Banks
- Cohort Studies
- Ethnicity
- Fetal Blood
- Gene Frequency
- Genetic Loci
- Genotype
- HLA Antigens
- High-Throughput Nucleotide Sequencing
- Humans
- Organ Transplantation
- Polymorphism, Genetic
- United Kingdom