Article
Common, Intermediate and Well-Documented HLA Alleles in the Brazilian Population: An Analysis of the Brazilian Bone Marrow Donor Registry (REDOME).
HLA - 1 Feb 2025
da Silva Jose Samuel, Visentainer Jeane Eliete Laguila, Fabreti-Oliveira Raquel Aparecida, de Souza Felipe Carlos Brito, Silva Marcio Nogueira Pereira, da Costa Sena Alexandre, Goldenstein Monica, Claudino Renata Esterque, de Souza Mendonça-Mattos Patricia Jeanne, Motta Juliana Pessanha Rodrigues, Secco Danielle Angst, Oliveira Danielli, Porto Luís Cristóvão
Abstract excerpt
This study investigates the HLA allele diversity in Brazil, a reflection of the country's unique history of population admixture. The international comparison of findings emphasises the importance of incorporating underrepresented populations into global HLA databases. We present a comprehensive analysis of HLA alleles within the Brazilian population, utilising high-resolution sequencing data from 298,000...
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