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Article

High Resolution HLA-A, HLA-B, and HLA-C Allele Frequencies in Romanian Hematopoietic Stem Cell Donors.

International journal of molecular sciences - 14 Aug 2024

Caragea Andreea Mirela, Ursu Radu-Ioan, Maruntelu Ion, Tizu Maria, Constantinescu Alexandra-Elena, Tălăngescu Adriana, Constantinescu Ileana

Abstract excerpt

The HLA genes are associated with various autoimmune pathologies, with the control of the immune response also being significant in organs and cells transplantation. The aim of the study is to identify the HLA-A, HLA-B, and HLA-C alleles frequencies in the analyzed Romanian cohort. We performed HLA typing using next-generation sequencing (NGS) in a Romanian cohort to estimate class I HLA allele frequencies up to...

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Hematopoietic Stem Cell Transplantation
Hematopoietic Stem Cells
Histocompatibility Testing
HLA-A Antigens
HLA-B Antigens

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PMID: 39201523
DOI: 10.3390/ijms25168837
PMCID: PMC11354460

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