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Article

Novel DNA methylation loci and genes showing pleiotropic association with Alzheimer's dementia: a network Mendelian randomization analysis.

Epigenetics - 1 Jan 2000

Liu Di, Wang Youxin, Jing Huiquan, Meng Qun, Yang Jingyun

Abstract excerpt

Previous genome-wide association studies (GWAS) have identified potential genetic variants involved in the risk of Alzheimer's dementia, but their underlying biological interpretation remains largely unclear. In addition, the effects of DNA methylation and gene expression on Alzheimer's dementia are not well understood. A network summary data-based Mendelian randomization (SMR) analysis was performed integrating...

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Identifiers

PMID: 34461811
DOI: 10.1080/15592294.2021.1959735
PMCID: PMC9336475

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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