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Article

Summary-data-based Mendelian Randomization Analysis Identifies Nominal Evidence for Association of N6-Methyladenosine Genetic Variation with Alzheimer's Disease.

Omics : a journal of integrative biology - 1 Jan 2026

Rahman Md Rezanur, Yang Yuanhao, Gratten Jacob, Anggono Victor, Widagdo Jocelyn

Abstract excerpt

N6-methyladenosine (m6A) is an abundant post-transcriptional RNA modification that critically regulates brain function. Dysregulation of m6A signaling has been implicated in several neurological diseases, including Alzheimer's disease (AD). However, whether genetic variation associated with the risk of AD is mediated via m6A-dependent gene regulation is currently unknown. Here we investigated the association of...

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PMID: 41449533
DOI: 10.1177/15578100251408263

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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