Article
Association between IL-18 gene polymorphisms and Hashimoto thyroiditis.
Molecular biology reports - 1 Oct 2021
Karakaya Dilek, Çakmak Genc Gunes, Karakas Celik Sevim, Aktas Tugba, Bayraktaroglu Taner, Dursun Ahmet
Abstract excerpt
BACKGROUND: Hashimoto's thyroiditis (HT), which is also called lymphocytic thyroiditis, is the most frequent autoimmune thyroid disease (AITD), in which T helper-1 lymphocytes mediate the disease. IL-18 is expressed in thyroid follicular cells (TFCs) during HT. The findings of studies aimed at investigating the relationship between IL-18 and HT are highly contradictory. In this study, we aimed to investigate the...
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