Article
Polymorphism of IL37 gene as a protective factor for autoimmune thyroid disease.
Journal of molecular endocrinology - 1 Dec 2015
Yan Ni, Meng Shuai, Song Rong-Hua, Qin Qiu, Wang Xuan, Yao Qiuming, Jiang Yanfei, Jiang Wenjuan, Shi Liangfeng, Xu Jian, Zhang Jinan
Abstract excerpt
Autoimmune thyroid disease (AITD) comprises Graves' disease (GD) and Hashimoto's thyroiditis (HT). IL37 has been recently proved to be a natural suppressor for innate immunity and acquired immunity. Therefore, this study was conducted to identify the association of IL37 genetic polymorphisms with AITD in Chinese Han population. Polymorphisms of rs3811046/rs3811047/rs2723176/rs272186 in the IL37 gene were assessed...
Read the complete abstract on PubMed