Article
The combination of ınterleukin-10 -1082 and tumor necrosis factor α -308 or ınterleukin-6 -174 genes polymorphisms suggests an association with susceptibility to Hashimoto's thyroiditis.
International immunopharmacology - 1 Apr 2012
Baki Merve, Akman Fevziye E, Vural Pervin, Doğru-Abbasoğlu Semra, Özderya Ayşenur, Karadağ Berrin, Uysal Müjdat
Abstract excerpt
BACKGROUND: The etiopathogenesis of Hashimoto's thyroiditis (HT) has not been clearly elucidated although the role of chronical inflammation and endothelial dysfunction has been established. The imbalance between pro- and anti-inflammatory cytokines may play a role in the etiology. The aim of the present study was to investigate whether cytokine gene polymorphisms are associated with HT, and to evaluate the...
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