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Article

A gene-disease association study of IL18 in thyroid cancer: genotype and haplotype analyses.

Endocrine - 1 Dec 2015

Abdolahi Farzan, Dabbaghmanesh Mohammad Hossein, Haghshenas Mohammad Reza, Ghaderi Abbas, Erfani Nasrollah

Abstract excerpt

Thyroid cancer is the most common malignancy of the endocrine system, and genetic factors have been shown to be associated with its risk. Interleukin-18 (IL-18) is a pleiotropic pro-inflammatory cytokine that induces IFN-γ production and is involved in T helper type 1 development. To determine the role of IL-18 gene in thyroid cancer susceptibility, we conducted a case-control study, and genotyped five single...

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Identifiers

PMID: 26041375
DOI: 10.1007/s12020-015-0623-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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