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Article

The IL18 gene and Hashimoto thyroiditis in children.

Human immunology - 1 Jan 2013

Huang Chi-Yu, Ting Wei-Hsin, Lo Fu-Sung, Wu Yi-Lei, Chang Tzu-Yang, Chan Hui-Wen, Lin Wen-Shan, Chen Wei-Fang, Lien Ya-Ping, Lee Yann-Jinn

Abstract excerpt

Interleukin 18 (IL18) stimulates interferon-γ production in Th1 cells which are prominent in the thyroid of Hashimoto thyroiditis (HT). We investigated the association between the IL18 gene and HT. There were 116 children with HT and 1272 controls. rs187238 and rs1946518 in the promoter region of the IL18 gene were genotyped. Differences in genotype, allele, carrier, and haplotype distributions between patients...

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Identifiers

PMID: 23073298
DOI: 10.1016/j.humimm.2012.10.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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