Article
Association of interleukin-17A and -17F gene single-nucleotide polymorphisms with autoimmune thyroid diseases.
Autoimmunity - 1 Nov 2012
Yan Ni, Yu Yong-Liang, Yang Jing, Qin Qiu, Zhu Yuan-Feng, Wang Xuan, Song Rong-Hua, Zhang Jin-An
Abstract excerpt
Th17 lymphocyte and its relative cytokines have been shown to play an important role in autoimmune thyroid diseases (AITD). The aim of this study was to investigate the association between IL-17A and IL-17F gene polymorphisms and two main types of AITD, Graves' disease (GD) and Hashimoto's thyroiditis (HT). Whole blood specimens and clinical data were collected from 508 AITD patients (326 with GD and 182 with HT)...
Topics
- Adolescent
- Adult
- Aged
- Alleles
- Asian People
- Autoimmune Diseases
- Base Sequence
- Case-Control Studies
- Child
- Child, Preschool
- Female
- Gene Frequency
